| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Pig/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-EDG8/SPPR1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:2000.WB: Approx 38kDa band observed in Human Brain (Frontal Cortex and Amygdala) lysates (calculated MW of 41.8kDa according to NP_110387.1). Recommended concentration: 1-3µg/ml. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
S1PR5 |
| Gene ID: |
53637 |
| Uniprot ID: |
S1PR5_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_110387.1 |
| Immunogen Sequence: |
SGSERSSPQRDGLD |
| Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. |
| Protein Name | Sphingosine 1-Phosphate Receptor 5S1p Receptor 5S1p5Endothelial Differentiation G-Protein-Coupled Receptor 8Sphingosine 1-Phosphate Receptor Edg-8S1p Receptor Edg-8 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-419408 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 5 antibodyAnti-S1p Receptor 5 antibodyAnti-S1p5 antibodyAnti-Endothelial Differentiation G-Protein-Coupled Receptor 8 antibodyAnti-Sphingosine 1-Phosphate Receptor Edg-8 antibodyAnti-S1p Receptor Edg-8 antibodyAnti-S1PR5 antibodyAnti-EDG8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
