Host: | Goat |
Applications: | Pep-ELISA/WB |
Reactivity: | Human/Pig/Cow |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-EDG8/SPPR1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:2000. WB: Approx 38kDa band observed in Human Brain (Frontal Cortex and Amygdala) lysates (calculated MW of 41.8kDa according to NP_110387.1). Recommended concentration: 1-3µg/ml. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | S1PR5 |
Gene ID: | 53637 |
Uniprot ID: | S1PR5_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_110387.1 |
Immunogen Sequence: | SGSERSSPQRDGLD |
Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. |
Protein Name | Sphingosine 1-Phosphate Receptor 5 S1p Receptor 5 S1p5 Endothelial Differentiation G-Protein-Coupled Receptor 8 Sphingosine 1-Phosphate Receptor Edg-8 S1p Receptor Edg-8 |
Database Links | Reactome: R-HSA-418594 Reactome: R-HSA-419408 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 5 antibody Anti-S1p Receptor 5 antibody Anti-S1p5 antibody Anti-Endothelial Differentiation G-Protein-Coupled Receptor 8 antibody Anti-Sphingosine 1-Phosphate Receptor Edg-8 antibody Anti-S1p Receptor Edg-8 antibody Anti-S1PR5 antibody Anti-EDG8 antibody |
Information sourced from Uniprot.org