• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-EDEM2 antibody (C-Term) (STJ92823)

SKU:
STJ92823

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ER degradation-enhancing alpha-mannosidase-like protein 2 (C-Term) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EDEM2
Gene ID: 55741
Uniprot ID: EDEM2_HUMAN
Immunogen Region: C-Term
Specificity: EDEM2 Polyclonal Antibody detects endogenous levels of EDEM2 protein.
Immunogen: Synthesized peptide derived from the C-terminal region of human EDEM2.
Post Translational Modifications N-glycosylated.
Function Involved in the endoplasmic reticulum-associated degradation (ERAD) pathway that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. May initiate ERAD by promoting the first mannose trimming step of ERAD substrates, from Man9GlcNAc2 to Man8GlcNAc2. Seems to recognize and bind to exposed hydrophobic regions in target proteins.
Protein Name Er Degradation-Enhancing Alpha-Mannosidase-Like Protein 2
Database Links Reactome: R-HSA-901032
Reactome: R-HSA-9694548
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Antibody Names Anti-Er Degradation-Enhancing Alpha-Mannosidase-Like Protein 2 antibody
Anti-EDEM2 antibody
Anti-C20orf31 antibody
Anti-C20orf49 antibody
Anti-UNQ573 antibody
Anti-PRO1135 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance