| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EDARADD |
| Gene ID: | 128178 |
| Uniprot ID: | EDAD_HUMAN |
| Immunogen Region: | 1-215 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human EDARADD (NP_665860.2). |
| Immunogen Sequence: | MGLRTTKQMGRGTKAPGHQE DHMVKEPVEDTDPSTLSFNM SDKYPIQDTELPKAEECDTI TLNCPRNSDMKNQGEENGFP DSTGDPLPEISKDNSCKENC TCSSCLLRAPTISDLLNDQD LLDVIRIKLDPCHPTVKNWR NFASKWGMSYDELCFLEQRP QSPTLEFLLRNSQRTVGQLM ELCRLYHRADVEKVLRRWVD EEWPKRERGDPSRHF |
| Tissue Specificity | Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis. |
| Function | Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B. |
| Protein Name | Ectodysplasin-A Receptor-Associated Adapter ProteinEdar-Associated Death Domain ProteinProtein Crinkled Homolog |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ectodysplasin-A Receptor-Associated Adapter Protein antibodyAnti-Edar-Associated Death Domain Protein antibodyAnti-Protein Crinkled Homolog antibodyAnti-EDARADD antibody |
Information sourced from Uniprot.org