• Western blot analysis of various lysates using EDARADD Rabbit polyclonal antibody (STJ118395) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-EDARADD antibody (1-215) (STJ118395)

SKU:
STJ118395

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EDARADD (1-215) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EDARADD
Gene ID: 128178
Uniprot ID: EDAD_HUMAN
Immunogen Region: 1-215
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human EDARADD (NP_665860.2).
Immunogen Sequence: MGLRTTKQMGRGTKAPGHQE DHMVKEPVEDTDPSTLSFNM SDKYPIQDTELPKAEECDTI TLNCPRNSDMKNQGEENGFP DSTGDPLPEISKDNSCKENC TCSSCLLRAPTISDLLNDQD LLDVIRIKLDPCHPTVKNWR NFASKWGMSYDELCFLEQRP QSPTLEFLLRNSQRTVGQLM ELCRLYHRADVEKVLRRWVD EEWPKRERGDPSRHF
Tissue Specificity Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis.
Function Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B.
Protein Name Ectodysplasin-A Receptor-Associated Adapter Protein
Edar-Associated Death Domain Protein
Protein Crinkled Homolog
Database Links Reactome: R-HSA-5669034
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Ectodysplasin-A Receptor-Associated Adapter Protein antibody
Anti-Edar-Associated Death Domain Protein antibody
Anti-Protein Crinkled Homolog antibody
Anti-EDARADD antibody

Information sourced from Uniprot.org

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