Anti-EDA antibody (120-170 aa) (STJ97656)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human EDA at the amino acid range 120-170
General Information
| Short Description | Rabbit polyclonal anti-Ectodysplasin-A (120-170 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EDA |
| Gene ID | 1896 |
| Uniprot ID | EDA_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human EDA at the amino acid range 120-170 |
| Immunogen Region | 120-170 aa |
| Specificity | EDA Polyclonal Antibody detects endogenous levels of EDA protein. |
Additional Info
| Post Translational Modifications | N-glycosylated. Processing by furin produces a secreted form. |
| Function | Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R. May also play a role in cell adhesion. Isoform 1: Binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor EDA2R. Isoform 3: Binds only to the receptor EDA2R. |
| Protein Name | Ectodysplasin-AEctodermal Dysplasia ProteinEda Protein Cleaved Into - Ectodysplasin-A - Membrane Form - Ectodysplasin-A - Secreted Form |
| Database Links | Reactome: R-HSA-5669034 Q92838-3 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinEctodysplasin-ASecreted Form: Secreted |
| Alternative Antibody Names | Anti-Ectodysplasin-A antibodyAnti-Ectodermal Dysplasia Protein antibodyAnti-Eda Protein Cleaved Into - Ectodysplasin-A - Membrane Form - Ectodysplasin-A - Secreted Form antibodyAnti-EDA antibodyAnti-ED1 antibodyAnti-EDA2 antibody |
Information sourced from Uniprot.org