• Immunohistochemical analysis of paraffin-embedded human-breast-cancer, antibody was diluted at 1:200
  • Western blot analysis of mouse-lung mouse-heart mouse-liver lysis using EDA antibody. Antibody was diluted at 1:1000. Secondary antibody was diluted at 1:20000

Anti-EDA antibody (120-170 aa) (STJ97656)

SKU:
STJ97656

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ectodysplasin-A (120-170 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EDA
Gene ID: 1896
Uniprot ID: EDA_HUMAN
Immunogen Region: 120-170 aa
Specificity: EDA Polyclonal Antibody detects endogenous levels of EDA protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human EDA at the amino acid range 120-170
Post Translational Modifications N-glycosylated. Processing by furin produces a secreted form.
Function Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R. May also play a role in cell adhesion. Isoform 1: Binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor EDA2R. Isoform 3: Binds only to the receptor EDA2R.
Protein Name Ectodysplasin-A
Ectodermal Dysplasia Protein
Eda Protein Cleaved Into - Ectodysplasin-A - Membrane Form - Ectodysplasin-A - Secreted Form
Database Links Reactome: R-HSA-5669034 Q92838-3
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Ectodysplasin-A
Secreted Form: Secreted
Alternative Antibody Names Anti-Ectodysplasin-A antibody
Anti-Ectodermal Dysplasia Protein antibody
Anti-Eda Protein Cleaved Into - Ectodysplasin-A - Membrane Form - Ectodysplasin-A - Secreted Form antibody
Anti-EDA antibody
Anti-ED1 antibody
Anti-EDA2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance