| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ECM1 |
| Gene ID: | 1893 |
| Uniprot ID: | ECM1_HUMAN |
| Immunogen Region: | 280-405 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 280-405 of human ECM1 (NP_004416.2). |
| Immunogen Sequence: | QLRACPSHQPDISSGLELPF PPGVPTLDNIKNICHLRRFR SVPRNLPATDPLQRELLALI QLEREFQRCCRQGNNHTCTW KAWEDTLDKYCDREYAVKTH HHLCCRHPPSPTRDECFARR APYPNY |
| Tissue Specificity | Expressed in breast cancer tissues. Little or no expression observed in normal breast tissues. Expressed in skin.wide expression is observed throughout the dermis with minimal expression in the epidermis. |
| Function | Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. |
| Protein Name | Extracellular Matrix Protein 1Secretory Component P85 |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Extracellular Matrix Protein 1 antibodyAnti-Secretory Component P85 antibodyAnti-ECM1 antibody |
Information sourced from Uniprot.org