| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
EBF4 |
| Gene ID: |
57593 |
| Uniprot ID: |
COE4_HUMAN |
| Immunogen Region: |
50-150 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human EBF4 (NP_001103984.1). |
| Immunogen Sequence: |
HFEKQPPSNLRKSNFFHFVL AMYDRQGQPVEVERTAFIDF VEKDREPGAEKTNNGIHYRL RLVYNNGLRTEQDLYVRLID SMSKQAIIYEGQDKNPEMCR V |
| Tissue Specificity | Most highly expressed in cytotoxic NK cells, especially CD16(+) NK cells, followed by CD8(+) T-cells. |
| Function | Transcription factor. Binds to specific sequence motif 5'-CCCNNGGAG-3' in regulatory elements of putative target immunoregulatory genes such as NKG7, GZMA, and TBX21. Positively modulates transcription of NKG7. May play a role in regulating FAS/CD95-mediated apoptosis in cytotoxic NK cells and T-cells, probably downstream of interleukin IL2 signaling. |
| Protein Name | Transcription Factor Coe4Early B-Cell Factor 4Ebf-4Olf-1/Ebf-Like 4O/E-4Oe-4 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Coe4 antibodyAnti-Early B-Cell Factor 4 antibodyAnti-Ebf-4 antibodyAnti-Olf-1/Ebf-Like 4 antibodyAnti-O/E-4 antibodyAnti-Oe-4 antibodyAnti-EBF4 antibodyAnti-COE4 antibodyAnti-KIAA1442 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
