| Tissue Specificity | Most highly expressed in cytotoxic NK cells, especially CD16(+) NK cells, followed by CD8(+) T-cells. |
| Function | Transcription factor. Binds to specific sequence motif 5'-CCCNNGGAG-3' in regulatory elements of putative target immunoregulatory genes such as NKG7, GZMA, and TBX21. Positively modulates transcription of NKG7. May play a role in regulating FAS/CD95-mediated apoptosis in cytotoxic NK cells and T-cells, probably downstream of interleukin IL2 signaling. |
| Protein Name | Transcription Factor Coe4Early B-Cell Factor 4Ebf-4Olf-1/Ebf-Like 4O/E-4Oe-4 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Coe4 antibodyAnti-Early B-Cell Factor 4 antibodyAnti-Ebf-4 antibodyAnti-Olf-1/Ebf-Like 4 antibodyAnti-O/E-4 antibodyAnti-Oe-4 antibodyAnti-EBF4 antibodyAnti-COE4 antibodyAnti-KIAA1442 antibody |
Information sourced from Uniprot.org
