| Tissue Specificity | High expression in heart, liver, brain and pancreas.moderate in placenta, skeletal muscle and kidney.low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients. |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
| Protein Name | Dynein Light Chain Roadblock-Type 1Bithoraxoid-Like ProteinBlpDynein Light Chain 2a - CytoplasmicDynein-Associated Protein Km23Roadblock Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-5620924 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Dynein Light Chain Roadblock-Type 1 antibodyAnti-Bithoraxoid-Like Protein antibodyAnti-Blp antibodyAnti-Dynein Light Chain 2a - Cytoplasmic antibodyAnti-Dynein-Associated Protein Km23 antibodyAnti-Roadblock Domain-Containing Protein 1 antibodyAnti-DYNLRB1 antibodyAnti-BITH antibodyAnti-DNCL2A antibodyAnti-DNLC2A antibodyAnti-ROBLD1 antibodyAnti-HSPC162 antibody |
Information sourced from Uniprot.org
