| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DYNLRB1 (1-63) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DYNLRB1 |
| Gene ID: |
83658 |
| Uniprot ID: |
DLRB1_HUMAN |
| Immunogen Region: |
1-63 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-63 of human DYNLRB1 (NP_001268656.1). |
| Immunogen Sequence: |
MDNPTTTQYASLMHSFILKA RSTVRDIDPQNDLTFLRIRS KKNEIMVAPDKDYFLIVIQN PTE |
| Tissue Specificity | High expression in heart, liver, brain and pancreas.moderate in placenta, skeletal muscle and kidney.low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients. |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
| Protein Name | Dynein Light Chain Roadblock-Type 1Bithoraxoid-Like ProteinBlpDynein Light Chain 2a - CytoplasmicDynein-Associated Protein Km23Roadblock Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-5620924 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Dynein Light Chain Roadblock-Type 1 antibodyAnti-Bithoraxoid-Like Protein antibodyAnti-Blp antibodyAnti-Dynein Light Chain 2a - Cytoplasmic antibodyAnti-Dynein-Associated Protein Km23 antibodyAnti-Roadblock Domain-Containing Protein 1 antibodyAnti-DYNLRB1 antibodyAnti-BITH antibodyAnti-DNCL2A antibodyAnti-DNLC2A antibodyAnti-ROBLD1 antibodyAnti-HSPC162 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
