• Western blot analysis of extracts of various cell lines, using DYNC2LI1 antibody (STJ26842) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-DYNC2LI1 antibody (1-352) (STJ26842)

SKU:
STJ26842

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DYNC2LI1 (1-352) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DYNC2LI1
Gene ID: 51626
Uniprot ID: DC2L1_HUMAN
Immunogen Region: 1-352
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human DYNC2LI1 (NP_001180393.1).
Immunogen Sequence: MPSETLWEIAKAEVEKRGIN GSEGDGAEIAEKFVFFIGSK NGGKTTIILRCLDRDEPPKP TLALEYTYGRRAKGHNTPKD IAHFWELGGGTSLLDLISIP ITGDTLRTFSLVLVLDLSKP NDLWPTMENLLQATKSHVDK VIMKLGKTNAKAVSEMRQKI WNNMPKDHPQDHELIDPFPV PLVIIGSKYDVFQDFESEKR KVICKTLRFVAHYYGASLMF TSKSEALLLKIRGVINQLA
Tissue Specificity Expressed in bone, brain, kidney, and cartilage. Lower expression in heart, liver, lung, placenta and thymus.
Function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system, facilitating the assembly of these organelles. Involved in the regulation of ciliary length.
Protein Name Cytoplasmic Dynein 2 Light Intermediate Chain 1
Dynein 2 Light Intermediate Chain
Database Links Reactome: R-HSA-5620924
Cellular Localisation Golgi Apparatus
Cytoplasm
Cell Projection
Cilium
Cytoskeleton
Cilium Basal Body
Cilium Axoneme
Microtubule Organizing Center
Centrosome
Localizes To The Apical Cytoplasm
Alternative Antibody Names Anti-Cytoplasmic Dynein 2 Light Intermediate Chain 1 antibody
Anti-Dynein 2 Light Intermediate Chain antibody
Anti-DYNC2LI1 antibody
Anti-D2LIC antibody
Anti-LIC3 antibody
Anti-CGI-60 antibody

Information sourced from Uniprot.org

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