• Western blot analysis of 1) HepG2, 2) 3T3, 3) Rat Heart Tissue with DUSP6 Rabbit pAb diluted at 1:3,000.

Anti-DUSP6 antibody (STJ197401)

SKU:
STJ197401

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dual specificity protein phosphatase 6 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-3000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DUSP6
Gene ID: 1848
Uniprot ID: DUS6_HUMAN
Specificity: DUSP6 Rabbit Polyclonal detects endogenous levels of DUSP6
Immunogen: Synthetic Peptide of DUSP6
Function Inactivates MAP kinases. Has a specificity for the ERK family. Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia. Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain. Promotes cell differentiation by regulating MAPK1/MAPK3 activity and regulating the expression of AP1 transcription factors.
Protein Name Dual Specificity Protein Phosphatase 6
Dual Specificity Protein Phosphatase Pyst1
Mitogen-Activated Protein Kinase Phosphatase 3
Map Kinase Phosphatase 3
Mkp-3
Database Links Reactome: R-HSA-112409
Reactome: R-HSA-202670
Reactome: R-HSA-5675221
Reactome: R-HSA-9652817
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Dual Specificity Protein Phosphatase 6 antibody
Anti-Dual Specificity Protein Phosphatase Pyst1 antibody
Anti-Mitogen-Activated Protein Kinase Phosphatase 3 antibody
Anti-Map Kinase Phosphatase 3 antibody
Anti-Mkp-3 antibody
Anti-DUSP6 antibody
Anti-MKP3 antibody
Anti-PYST1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance