Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat/Monkey |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Dual specificity protein phosphatase 4 (81-130) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DUSP4 |
Gene ID: |
1846 |
Uniprot ID: |
DUS4_HUMAN |
Immunogen Region: |
81-130 |
Specificity: |
MKP-2 Polyclonal Antibody detects endogenous levels of MKP-2 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human DUSP4. AA range:81-130 |
Post Translational Modifications | Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein. |
Function | Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. |
Protein Name | Dual Specificity Protein Phosphatase 4Dual Specificity Protein Phosphatase Hvh2Mitogen-Activated Protein Kinase Phosphatase 2Map Kinase Phosphatase 2Mkp-2 |
Database Links | Reactome: R-HSA-112409Reactome: R-HSA-202670Reactome: R-HSA-5675221 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 4 antibodyAnti-Dual Specificity Protein Phosphatase Hvh2 antibodyAnti-Mitogen-Activated Protein Kinase Phosphatase 2 antibodyAnti-Map Kinase Phosphatase 2 antibodyAnti-Mkp-2 antibodyAnti-DUSP4 antibodyAnti-MKP2 antibodyAnti-VH2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance