• Western blot analysis of various lysates, using MKP1 Rabbit polyclonal antibody (STJ11105430) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Negative control (NC) :THP-1Exposure time: 3s.

Anti-DUSP1 antibody (267-367) (STJ11105430)

SKU:
STJ11105430

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dual Specificity Protein Phosphatase 1 (267-367) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DUSP1
Gene ID: 1843
Uniprot ID: DUS1_HUMAN
Immunogen Region: 267-367
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 267-367 of human MKP1 (NP_004408.1).
Immunogen Sequence: TICLAYLMRTNRVKLDEAFE FVKQRRSIISPNFSFMGQLL QFESQVLAPHCSAEAGSPAM AVLDRGTSTTTVFNFPVSIP VHSTNSALSYLQSPITTSPS C
Tissue Specificity Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
Post Translational Modifications Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation.
Function Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Protein Name Dual Specificity Protein Phosphatase 1
Dual Specificity Protein Phosphatase Hvh1
Mitogen-Activated Protein Kinase Phosphatase 1
Map Kinase Phosphatase 1
Mkp-1
Protein-Tyrosine Phosphatase Cl100
Database Links Reactome: R-HSA-112409
Reactome: R-HSA-5675221
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Dual Specificity Protein Phosphatase 1 antibody
Anti-Dual Specificity Protein Phosphatase Hvh1 antibody
Anti-Mitogen-Activated Protein Kinase Phosphatase 1 antibody
Anti-Map Kinase Phosphatase 1 antibody
Anti-Mkp-1 antibody
Anti-Protein-Tyrosine Phosphatase Cl100 antibody
Anti-DUSP1 antibody
Anti-CL100 antibody
Anti-MKP1 antibody
Anti-PTPN10 antibody
Anti-VH1 antibody

Information sourced from Uniprot.org

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