Anti-DTNB antibody (STJA0008972)

SKU:
STJA0008972
£49.00 - £261.00
Processing The item has been added

Short Description :Rabbit polyclonal anti-Dystrobrevin beta for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:DTNB
Gene ID:1838
Uniprot ID:DTNB_HUMAN
Immunogen:Synthesized peptide derived from human DTNB
Specificity:This antibody detects endogenous levels of DTNB at Human, Mouse, Rat
Post Translational Modifications Phosphorylated by PKA. Phosphorylation at Thr-11 alters the interaction with KIF5A.
Function Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids. May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation. May be required for proper maturation and function of a subset of inhibitory synapses.
Protein Name Dystrobrevin Beta
Dtn-B
Beta-Dystrobrevin
Database Links Reactome: R-HSA-9913351
Cellular Localisation Cytoplasm
Postsynaptic Density
Cell Projection
Dendrite
Basal Cell Membrane
Postsynapse
Nucleus
Localized At Inhibitory Synapses On The Dendrites Of Cerebellar Purkinje Cells
Alternative Antibody Names Anti-Dystrobrevin Beta antibody
Anti-Dtn-B antibody
Anti-Beta-Dystrobrevin antibody
Anti-DTNB antibody

Information sourced from Uniprot.org