Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Desmoglein-2 (401-450 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000ELISA 1:40000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DSG2 |
Gene ID: |
1829 |
Uniprot ID: |
DSG2_HUMAN |
Immunogen Region: |
401-450 aa |
Specificity: |
Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human DSG2 at the amino acid range 401-450 |
Post Translational Modifications | Palmitoylated by ZDHHC5 at the plasma membrane. |
Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
Protein Name | Desmoglein-2Cadherin Family Member 5Hdgc |
Database Links | Reactome: R-HSA-351906Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9013404Reactome: R-HSA-9013408Reactome: R-HSA-9013423 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
Alternative Antibody Names | Anti-Desmoglein-2 antibodyAnti-Cadherin Family Member 5 antibodyAnti-Hdgc antibodyAnti-DSG2 antibodyAnti-CDHF5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance