| Short Description : | Rabbit polyclonal anti-Desmoglein-1 (30-90 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-P 1:500-200ELISA 1:10000-20000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DSG1 |
| Gene ID: | 1828 |
| Uniprot ID: | DSG1_HUMAN |
| Immunogen: | Synthetic peptide from the human protein at the amino acid range 30-90 |
| Immunogen Region: | 30-90 aa |
| Specificity: | The antibody detects endogenous Dsg1 |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Protein Name | Desmoglein-1Cadherin Family Member 4Desmosomal Glycoprotein 1Dg1DgiPemphigus Foliaceus Antigen |
| Database Links | Reactome: R-HSA-351906Reactome: R-HSA-6798695Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9696264Reactome: R-HSA-9696270 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosomeCytoplasmNucleus |
| Alternative Antibody Names | Anti-Desmoglein-1 antibodyAnti-Cadherin Family Member 4 antibodyAnti-Desmosomal Glycoprotein 1 antibodyAnti-Dg1 antibodyAnti-Dgi antibodyAnti-Pemphigus Foliaceus Antigen antibodyAnti-DSG1 antibodyAnti-CDHF4 antibody |
Information sourced from Uniprot.org
