• STJ71827 Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml) , showing cytoplasmic and Golgi apparatus staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml).
  • STJ71827 Immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml) , showing Golgi apparatus and some cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml).
  • STJ71827 Flow cytometric analysis of paraformaldehyde fixed Jurkat cells (blue line) , permeabilized with 0. 5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Anti-DSCR2/PSMG1 antibody (C-Term) (STJ71827)

SKU:
STJ71827-100

$409.73
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Host: Goat
Applications: Pep-ELISA/IF/FC
Reactivity: Human/Mouse/Rat/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-DSCR2/PSMG1 (C-Term) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IF-Strong expression of the protein seen in the cytoplasm and Golgi apparatus of A431 and U2OS cells. 10µg/ml
ELISA-antibody detection limit dilution 1:64000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PSMG1
Gene ID: 8624
Uniprot ID: PSMG1_HUMAN
Immunogen Region: C-Term
Accession Number: NP_003711.1; NP_982257.1; NP_001248753.1; NP_001307724.1
Specificity: This antibody is expected to recognize all reported isoforms (NP_003711.1; NP_982257.1;NP_001248753.1; NP_001307724.1)
Immunogen Sequence: KLMTTNEIQSNIYT
Post Translational Modifications Degraded by the proteasome upon completion of 20S proteasome maturation.
Function Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
Protein Name Proteasome Assembly Chaperone 1
Pac-1
Chromosome 21 Leucine-Rich Protein
C21-Lrp
Down Syndrome Critical Region Protein 2
Cellular Localisation Cytoplasm
Endoplasmic Reticulum
Alternative Antibody Names Anti-Proteasome Assembly Chaperone 1 antibody
Anti-Pac-1 antibody
Anti-Chromosome 21 Leucine-Rich Protein antibody
Anti-C21-Lrp antibody
Anti-Down Syndrome Critical Region Protein 2 antibody
Anti-PSMG1 antibody
Anti-C21LRP antibody
Anti-DSCR2 antibody
Anti-PAC1 antibody

Information sourced from Uniprot.org

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