Anti-DSC2 antibody [SAA1658] (STJA0020086)

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STJA0020086
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Desmocollin-2 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1658
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: DSC2
Gene ID: 1824
Uniprot ID: DSC2_HUMAN
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. May promote p38MAPK signaling activation that facilitates keratinocyte migration.
Protein Name Desmocollin-2
Cadherin Family Member 2
Desmocollin-3
Desmosomal Glycoprotein Ii
Desmosomal Glycoprotein Iii
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Desmosome
Alternative Antibody Names Anti-Desmocollin-2 antibody
Anti-Cadherin Family Member 2 antibody
Anti-Desmocollin-3 antibody
Anti-Desmosomal Glycoprotein Ii antibody
Anti-Desmosomal Glycoprotein Iii antibody
Anti-DSC2 antibody
Anti-CDHF2 antibody
Anti-DSC3 antibody

Information sourced from Uniprot.org

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