| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DSC2 (520-690) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DSC2 |
| Gene ID: |
1824 |
| Uniprot ID: |
DSC2_HUMAN |
| Immunogen Region: |
520-690 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 520-690 of human DSC2 (NP_077740.1). |
| Immunogen Sequence: |
IDENTGSIKVFRSLDREAET IKNGIYNITVLASDQGGRTC TGTLGIILQDVNDNSPFIPK KTVIICKPTMSSAEIVAVDP DEPIHGPPFDFSLESSTSEV QRMWRLKAINDTAARLSYQN DPPFGSYVVPITVRDRLGMS SVTSLDVTLCDCITENDCTH RVDPRIGGGGV |
| Tissue Specificity | Expressed in the heart (at protein level). |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. |
| Protein Name | Desmocollin-2Cadherin Family Member 2Desmocollin-3Desmosomal Glycoprotein IiDesmosomal Glycoprotein Iii |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
| Alternative Antibody Names | Anti-Desmocollin-2 antibodyAnti-Cadherin Family Member 2 antibodyAnti-Desmocollin-3 antibodyAnti-Desmosomal Glycoprotein Ii antibodyAnti-Desmosomal Glycoprotein Iii antibodyAnti-DSC2 antibodyAnti-CDHF2 antibodyAnti-DSC3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
