Anti-DRD2 nanobody [SAA1361] (STJN000151)

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STJN000151
£378.50 - £1,632.50
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Host: Alpaca
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-D (2 Dopamine Receptor is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1361
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: DRD2
Gene ID: 1813
Uniprot ID: DRD2_HUMAN
Post Translational Modifications Palmitoylated. Palmitoylation which is required for proper localization to the plasma membrane and stability of the receptor could be carried on by ZDHHC4, ZDHHC3 and ZDHHC8.
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5.
Protein Name D(2 Dopamine Receptor
Dopamine D2 Receptor
Database Links Reactome: R-HSA-390651
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Alternative Nanobody Names Anti-D(2 Dopamine Receptor nanobody
Anti-Dopamine D2 Receptor nanobody
Anti-DRD2 nanobody

Information sourced from Uniprot.org