| Short Description : | Rabbit polyclonal anti-DNA damage-regulated autophagy modulator protein 2 (57-107 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DRAM2 |
| Gene ID: | 128338 |
| Uniprot ID: | DRAM2_HUMAN |
| Immunogen: | Synthesized peptide derived from the human DRAM2 at the amino acid range 57-107 |
| Immunogen Region: | 57-107 aa |
| Specificity: | This antibody detects endogenous levels of DRAM2 at Human/Mouse/Rat |
| Function | Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1. |
| Protein Name | Dna Damage-Regulated Autophagy Modulator Protein 2Transmembrane Protein 77 |
| Database Links | |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane ProteinPhotoreceptor Inner SegmentApical Cell MembraneLocalized To Photoreceptor Inner Segments And To The Apical Surface Of Retinal Pigment Epithelial Cells |
| Alternative Antibody Names | Anti-Dna Damage-Regulated Autophagy Modulator Protein 2 antibodyAnti-Transmembrane Protein 77 antibodyAnti-DRAM2 antibodyAnti-TMEM77 antibodyAnti-PSEC0031 antibodyAnti-UNQ154 antibodyAnti-PRO180 antibody |
Information sourced from Uniprot.org
