| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DPYSL3 (440-520) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DPYSL3 |
| Gene ID: |
1809 |
| Uniprot ID: |
DPYL3_HUMAN |
| Immunogen Region: |
440-520 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 440-520 of human DPYSL3 (NP_001378.1). |
| Immunogen Sequence: |
RGAPLVVICQGKIMLEDGNL HVTQGAGRFIPCSPFSDYVY KRIKARRKMADLHAVPRGMY DGPVFDLTTTPKGGTPAGSA R |
| Tissue Specificity | Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord. |
| Post Translational Modifications | Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3. |
| Function | Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. |
| Protein Name | Dihydropyrimidinase-Related Protein 3Drp-3Collapsin Response Mediator Protein 4Crmp-4Unc-33-Like Phosphoprotein 1Ulip-1 |
| Database Links | Reactome: R-HSA-399956 |
| Cellular Localisation | CytoplasmCell ProjectionGrowth ConeColocalizes With Synaptic Vesicle Protein 2 In The Central Region Of The Growth Cone |
| Alternative Antibody Names | Anti-Dihydropyrimidinase-Related Protein 3 antibodyAnti-Drp-3 antibodyAnti-Collapsin Response Mediator Protein 4 antibodyAnti-Crmp-4 antibodyAnti-Unc-33-Like Phosphoprotein 1 antibodyAnti-Ulip-1 antibodyAnti-DPYSL3 antibodyAnti-CRMP4 antibodyAnti-DRP3 antibodyAnti-ULIP antibodyAnti-ULIP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
