Anti-DPEP1/MDP antibody (STJA0037904)

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STJA0037904
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Short Description :Rabbit monoclonal anti-DPEP1/MDP for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Purified
Dilution Range:IHC 1:100-1:200
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:DPEP1
Gene ID:1800
Uniprot ID:DPEP1_HUMAN
Immunogen:A synthesized peptide derived from human DPEP1
Tissue Specificity Expressed in lung and kidneys.
Function Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Also possesses beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem. Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
Protein Name Dipeptidase 1
Beta-Lactamase
Dehydropeptidase-I
Microsomal Dipeptidase
Renal Dipeptidase
Hrdp
Database Links Reactome: R-HSA-2142691
Reactome: R-HSA-5423646
Reactome: R-HSA-9664535
Cellular Localisation Apical Cell Membrane
Lipid-Anchor
Gpi-Anchor
Cell Projection
Microvillus Membrane
Brush Border Membrane
Alternative Antibody Names Anti-Dipeptidase 1 antibody
Anti-Beta-Lactamase antibody
Anti-Dehydropeptidase-I antibody
Anti-Microsomal Dipeptidase antibody
Anti-Renal Dipeptidase antibody
Anti-Hrdp antibody
Anti-DPEP1 antibody
Anti-MDP antibody
Anti-RDP antibody

Information sourced from Uniprot.org