| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein Dok-7 (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DOK7 |
| Gene ID: | 285489 |
| Uniprot ID: | DOK7_HUMAN |
| Immunogen Region: | 10-59 aa |
| Specificity: | Dok-7 Polyclonal Antibody detects endogenous levels of Dok-7 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DOK7 at the amino acid range 10-59 |
| Function | Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK. |
| Protein Name | Protein Dok-7Downstream Of Tyrosine Kinase 7 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSynapseAccumulates At Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Protein Dok-7 antibodyAnti-Downstream Of Tyrosine Kinase 7 antibodyAnti-DOK7 antibodyAnti-C4orf25 antibody |
Information sourced from Uniprot.org