Anti-DOHH antibody [R04-4I8] (STJA0034256)

SKU:
STJA0034256
£133.50 - £281.50
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Host: Rabbit
Applications: WB/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-DOHH for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R04-4I8
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
IP 1:20
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: DOHH
Gene ID: 83475
Uniprot ID: DOHH_HUMAN
Immunogen: A synthetic peptide of human DOHH
Function Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.
Protein Name Deoxyhypusine Hydroxylase
Hdohh
Deoxyhypusine Dioxygenase
Deoxyhypusine Monooxygenase
Heat-Like Repeat-Containing Protein 1
Database Links Reactome: R-HSA-204626
Cellular Localisation
Alternative Antibody Names Anti-Deoxyhypusine Hydroxylase antibody
Anti-Hdohh antibody
Anti-Deoxyhypusine Dioxygenase antibody
Anti-Deoxyhypusine Monooxygenase antibody
Anti-Heat-Like Repeat-Containing Protein 1 antibody
Anti-DOHH antibody
Anti-HLRC1 antibody

Information sourced from Uniprot.org