Anti-DOHH antibody [R04-4I8] (STJA0034256)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human DOHH
General Information
| Short Description | Rabbit monoclonal anti-DOHH for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-4I8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DOHH |
| Gene ID | 83475 |
| Uniprot ID | DOHH_HUMAN |
| Immunogen | A synthetic peptide of human DOHH |
Additional Info
| Function | Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. |
| Protein Name | Deoxyhypusine HydroxylaseHdohhDeoxyhypusine DioxygenaseDeoxyhypusine MonooxygenaseHeat-Like Repeat-Containing Protein 1 |
| Database Links | Reactome: R-HSA-204626 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Deoxyhypusine Hydroxylase antibodyAnti-Hdohh antibodyAnti-Deoxyhypusine Dioxygenase antibodyAnti-Deoxyhypusine Monooxygenase antibodyAnti-Heat-Like Repeat-Containing Protein 1 antibodyAnti-DOHH antibodyAnti-HLRC1 antibody |
Information sourced from Uniprot.org