• Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-DOCK2 antibody (Internal) (STJ92757)

SKU:
STJ92757

€57.50 - €282.50
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dedicator of cytokinesis protein 2 (Internal) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DOCK2
Gene ID: 1794
Uniprot ID: DOCK2_HUMAN
Immunogen Region: Internal
Specificity: DOCK 2 Polyclonal Antibody detects endogenous levels of DOCK 2 protein.
Immunogen: Synthesized peptide derived from the Internal region of human DOCK 2.
Function Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
Protein Name Dedicator Of Cytokinesis Protein 2
Database Links Reactome: R-HSA-164944
Reactome: R-HSA-6798695
Reactome: R-HSA-8980692
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013408
Reactome: R-HSA-983231
Cellular Localisation Endomembrane System
Peripheral Membrane Protein
Cytoplasm
Cytoskeleton
Colocalizes With F-Actin
Alternative Antibody Names Anti-Dedicator Of Cytokinesis Protein 2 antibody
Anti-DOCK2 antibody
Anti-KIAA0209 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance