| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNTT |
| Gene ID: | 1791 |
| Uniprot ID: | TDT_HUMAN |
| Immunogen Region: | 260-509 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-509 of human TdT (NP_004079.3). |
| Immunogen Sequence: | LKTSEKWFRMGFRTLSKVRS DKSLKFTRMQKAGFLYYEDL VSCVTRAEAEAVSVLVKEAV WAFLPDAFVTMTGGFRRGKK MGHDVDFLITSPGSTEDEEQ LLQKVMNLWEKKGLLLYYDL VESTFEKLRLPSRKVDALDH FQKCFLIFKLPRQRVDSDQS SWQEGKTWKAIRVDLVLCPY ERRAFALLGWTGSRQFERDL RRYATHERKMILDNHALYDK TKRIFLKAESEEEIFAHLG |
| Function | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
| Protein Name | Dna NucleotidylexotransferaseTerminal Addition EnzymeTerminal DeoxynucleotidyltransferaseTerminal Transferase |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Nucleotidylexotransferase antibodyAnti-Terminal Addition Enzyme antibodyAnti-Terminal Deoxynucleotidyltransferase antibodyAnti-Terminal Transferase antibodyAnti-DNTT antibodyAnti-TDT antibody |
Information sourced from Uniprot.org