Anti-DNTT antibody (260-509) (STJ28010)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DNTT (260-509) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DNTT |
| Gene ID | 1791 |
| Uniprot ID | TDT_HUMAN |
| Immunogen Region | 260-509 |
| Immunogen Sequence | LKTSEKWFRMGFRTLSKVRS DKSLKFTRMQKAGFLYYEDL VSCVTRAEAEAVSVLVKEAV WAFLPDAFVTMTGGFRRGKK MGHDVDFLITSPGSTEDEEQ LLQKVMNLWEKKGLLLYYDL VESTFEKLRLPSRKVDALDH FQKCFLIFKLPRQRVDSDQS SWQEGKTWKAIRVDLVLCPY ERRAFALLGWTGSRQFERDL RRYATHERKMILDNHALYDK TKRIFLKAESEEEIFAHLG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 260-509 of human TdT (NP_004079.3). |
Additional Info
| Function | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
| Protein Name | Dna NucleotidylexotransferaseTerminal Addition EnzymeTerminal DeoxynucleotidyltransferaseTerminal Transferase |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Nucleotidylexotransferase antibodyAnti-Terminal Addition Enzyme antibodyAnti-Terminal Deoxynucleotidyltransferase antibodyAnti-Terminal Transferase antibodyAnti-DNTT antibodyAnti-TDT antibody |
Information sourced from Uniprot.org