| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DNTT (260-509) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DNTT |
| Gene ID: |
1791 |
| Uniprot ID: |
TDT_HUMAN |
| Immunogen Region: |
260-509 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 260-509 of human TdT (NP_004079.3). |
| Immunogen Sequence: |
LKTSEKWFRMGFRTLSKVRS DKSLKFTRMQKAGFLYYEDL VSCVTRAEAEAVSVLVKEAV WAFLPDAFVTMTGGFRRGKK MGHDVDFLITSPGSTEDEEQ LLQKVMNLWEKKGLLLYYDL VESTFEKLRLPSRKVDALDH FQKCFLIFKLPRQRVDSDQS SWQEGKTWKAIRVDLVLCPY ERRAFALLGWTGSRQFERDL RRYATHERKMILDNHALYDK TKRIFLKAESEEEIFAHLG |
| Function | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
| Protein Name | Dna NucleotidylexotransferaseTerminal Addition EnzymeTerminal DeoxynucleotidyltransferaseTerminal Transferase |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Nucleotidylexotransferase antibodyAnti-Terminal Addition Enzyme antibodyAnti-Terminal Deoxynucleotidyltransferase antibodyAnti-Terminal Transferase antibodyAnti-DNTT antibodyAnti-TDT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
