| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Dynamin-binding protein (940-990 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNMBP |
| Gene ID: | 23268 |
| Uniprot ID: | DNMBP_HUMAN |
| Immunogen Region: | 940-990 aa |
| Specificity: | DNMBP Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein at the amino acid range 940-990 |
| Function | Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi. |
| Protein Name | Dynamin-Binding ProteinScaffold Protein Tuba |
| Database Links | Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmGolgi ApparatusGolgi StackCytoskeletonSynapseCell JunctionLocalizes To The Apical JunctionColocalizes With Tjp1 |
| Alternative Antibody Names | Anti-Dynamin-Binding Protein antibodyAnti-Scaffold Protein Tuba antibodyAnti-DNMBP antibodyAnti-ARHGEF36 antibodyAnti-KIAA1010 antibodyAnti-TUBA antibody |
Information sourced from Uniprot.org