| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNAJC19 |
| Gene ID: | 131118 |
| Uniprot ID: | TIM14_HUMAN |
| Immunogen Region: | 1-116 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-116 of human DNAJC19 (NP_660304.1). |
| Immunogen Sequence: | MASTVVAVGLTIAAAGFAGR YVLQAMKHMEPQVKQVFQSL PKSAFSGGYYRGGFEPKMTK REAALILGVSPTANKGKIRD AHRRIMLLNHPDKGGSPYIA AKINEAKDLLEGQAKK |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling. May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim14Dnaj Homolog Subfamily C Member 19 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim14 antibodyAnti-Dnaj Homolog Subfamily C Member 19 antibodyAnti-DNAJC19 antibodyAnti-TIM14 antibodyAnti-TIMM14 antibody |
Information sourced from Uniprot.org