| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Dynein axonemal heavy chain 8 (2086-2136 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNAH8 |
| Gene ID: | 1769 |
| Uniprot ID: | DYH8_HUMAN |
| Immunogen Region: | 2086-2136 aa |
| Specificity: | This antibody detects endogenous levels of human DYH8 |
| Immunogen: | Synthesized peptide derived from the human DYH8 at the amino acid range 2086-2136 |
| Function | Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility.implicated in sperm flagellar assembly. |
| Protein Name | Dynein Axonemal Heavy Chain 8Axonemal Beta Dynein Heavy Chain 8Ciliary Dynein Heavy Chain 8 |
| Cellular Localisation | CytoplasmCytoskeletonFlagellum AxonemeDetected In Sperm TailWith Almost Exclusive Localization To The Principal PieceAlso Detected In The Cytoplasm Of Primary Spermatocytes |
| Alternative Antibody Names | Anti-Dynein Axonemal Heavy Chain 8 antibodyAnti-Axonemal Beta Dynein Heavy Chain 8 antibodyAnti-Ciliary Dynein Heavy Chain 8 antibodyAnti-DNAH8 antibody |
Information sourced from Uniprot.org