| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Dynein axonemal heavy chain 8 (2086-2136 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DNAH8 |
| Gene ID: |
1769 |
| Uniprot ID: |
DYH8_HUMAN |
| Immunogen Region: |
2086-2136 aa |
| Specificity: |
This antibody detects endogenous levels of human DYH8 |
| Immunogen: |
Synthesized peptide derived from the human DYH8 at the amino acid range 2086-2136 |
| Function | Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility.implicated in sperm flagellar assembly. |
| Protein Name | Dynein Axonemal Heavy Chain 8Axonemal Beta Dynein Heavy Chain 8Ciliary Dynein Heavy Chain 8 |
| Cellular Localisation | CytoplasmCytoskeletonFlagellum AxonemeDetected In Sperm TailWith Almost Exclusive Localization To The Principal PieceAlso Detected In The Cytoplasm Of Primary Spermatocytes |
| Alternative Antibody Names | Anti-Dynein Axonemal Heavy Chain 8 antibodyAnti-Axonemal Beta Dynein Heavy Chain 8 antibodyAnti-Ciliary Dynein Heavy Chain 8 antibodyAnti-DNAH8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
