| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-DNAH8 (107-117) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Not yet tested-our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 515kDa according to NP_001362.2. Therefore we cannot |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | DNAH8 |
| Gene ID: | 1769 |
| Uniprot ID: | DYH8_HUMAN |
| Immunogen Region: | 107-117 |
| Accession Number: | NP_001362.2 |
| Immunogen Sequence: | EGTVKLKTIDN |
| Function | Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility.implicated in sperm flagellar assembly. |
| Protein Name | Dynein Axonemal Heavy Chain 8Axonemal Beta Dynein Heavy Chain 8Ciliary Dynein Heavy Chain 8 |
| Cellular Localisation | CytoplasmCytoskeletonFlagellum AxonemeDetected In Sperm TailWith Almost Exclusive Localization To The Principal PieceAlso Detected In The Cytoplasm Of Primary Spermatocytes |
| Alternative Antibody Names | Anti-Dynein Axonemal Heavy Chain 8 antibodyAnti-Axonemal Beta Dynein Heavy Chain 8 antibodyAnti-Ciliary Dynein Heavy Chain 8 antibodyAnti-DNAH8 antibody |
Information sourced from Uniprot.org
