• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-DMBT1 antibody (STJ192993)

SKU:
STJ192993

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Deleted in malignant brain tumors 1 protein is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-300
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DMBT1
Gene ID: 1755
Uniprot ID: DMBT1_HUMAN
Specificity: DMBT1 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Post Translational Modifications Highly N- and O-glycosylated. The O-glycans are heavily sulfated.
Function May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell.
Protein Name Deleted In Malignant Brain Tumors 1 Protein
Glycoprotein 340
Gp-340
Hensin
Salivary Agglutinin
Sag
Surfactant Pulmonary-Associated D-Binding Protein
Database Links Reactome: R-HSA-5683826
Cellular Localisation Secreted
Some Isoforms May Be Membrane-Bound
Localized To The Lumenal Aspect Of Crypt Cells In The Small Intestine
In The Colon
Seen In The Lumenal Aspect Of Surface Epithelial Cells
Formed In The Ducts Of Von Ebner Gland
And Released Into The Fluid Bathing The Taste Buds Contained In The Taste Papillae
Alternative Antibody Names Anti-Deleted In Malignant Brain Tumors 1 Protein antibody
Anti-Glycoprotein 340 antibody
Anti-Gp-340 antibody
Anti-Hensin antibody
Anti-Salivary Agglutinin antibody
Anti-Sag antibody
Anti-Surfactant Pulmonary-Associated D-Binding Protein antibody
Anti-DMBT1 antibody
Anti-GP340 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance