Western blot analysis using Dkk-1 monoclonal antibody against HEK293 (1) and DKK1-hIgGFc transfected HEK293 cell lysate (2).

Anti-DKK1 antibody [2H2] (STJ98000)

SKU:
STJ98000
£144.00 - £348.00
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Dickkopf-related protein 1 is suitable for use in Western Blot and ELISA research applications.
Clonality : Monoclonal
Clone ID : 2H2
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DKK1
Gene ID: 22943
Uniprot ID: DKK1_HUMAN
Specificity: Dkk-1 Monoclonal Antibody detects endogenous levels of Dkk-1 protein.
Immunogen: Purified recombinant fragment of Dkk-1 expressed in E. Coli.
Function Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity.
Protein Name Dickkopf-Related Protein 1
Dickkopf-1
Dkk-1
Hdkk-1
Sk
Database Links Reactome: R-HSA-201681
Reactome: R-HSA-3772470
Reactome: R-HSA-5339717
Cellular Localisation Secreted
Alternative Antibody Names Anti-Dickkopf-Related Protein 1 antibody
Anti-Dickkopf-1 antibody
Anti-Dkk-1 antibody
Anti-Hdkk-1 antibody
Anti-Sk antibody
Anti-DKK1 antibody
Anti-UNQ492 antibody
Anti-PRO1008 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ70585 Anti-DKK1 antibody (C-Term) (STJ70585) Goat Polyclonal Human/Mouse/Cow Pep-ELISA/WB/IF/IHC/FC
STJ23386 Anti-DKK1 antibody (32-266) (STJ23386) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJA0003594 Anti-c-FOS antibody (Full Length) [2H2] (STJA0003594) Mouse Monoclonal Bovine/Human/Mouse/Rat WB/IHC/ICC
STJ97257 Anti-DKK1 antibody (181-230 aa) (STJ97257) Rabbit Polyclonal Human/Mouse/Rat WB/IHC/IF/ELISA
STJ95982 Anti-GTF2H2 antibody (1-50 aa) (STJ95982) Rabbit Polyclonal Human/Mouse/Rat WB/IHC/IF/ELISA
STJ27210 Anti-GTF2H2C antibody (1-300) (STJ27210) Rabbit Polyclonal Human/Rat WB/IHC-P/ELISA
STJ98378 Anti-SARS-M antibody [2H2C4] (STJ98378) Mouse Monoclonal Human WB/ELISA
STJ98281 Anti-STYK1 antibody [2H2F10] (STJ98281) Mouse Monoclonal Human WB/IHC/IF/ELISA
STJ110596 Anti-GTF2H2C_2 antibody (1-260) (STJ110596) Rabbit Polyclonal Rat WB/ELISA
!