STJ70209 staining (0. 1µg/ml) of human kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-Dicarbonyl Reductase antibody (C-Term) (STJ70209)

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STJ70209-100
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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-Dicarbonyl Reductase (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:32000.
WB: Approx 26kDa band observed in human kidney, liver and testes lysates (calculated MW of 25.9kDa according to NP_057370.1). Recommended for use at 0.1-0.3µg/ml.
IHC: In paraffin embe
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: DCXR
Gene ID: 51181
Uniprot ID: DCXR_HUMAN
Immunogen Region: C-Term
Accession Number: NP_057370.1
Immunogen Sequence: GSTLPVEGGFWAC
Function Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Protein Name L-Xylulose Reductase
Xr
Carbonyl Reductase Ii
Dicarbonyl/L-Xylulose Reductase
Kidney Dicarbonyl Reductase
Kidcr
Short Chain Dehydrogenase/Reductase Family 20c Member 1
Sperm Surface Protein P34h
Database Links Reactome: R-HSA-5661270
Reactome: R-HSA-5662853
Cellular Localisation Membrane
Peripheral Membrane Protein
Probably Recruited To Membranes Via An Interaction With Phosphatidylinositol
Alternative Antibody Names Anti-L-Xylulose Reductase antibody
Anti-Xr antibody
Anti-Carbonyl Reductase Ii antibody
Anti-Dicarbonyl/L-Xylulose Reductase antibody
Anti-Kidney Dicarbonyl Reductase antibody
Anti-Kidcr antibody
Anti-Short Chain Dehydrogenase/Reductase Family 20c Member 1 antibody
Anti-Sperm Surface Protein P34h antibody
Anti-DCXR antibody
Anti-SDR20C1 antibody

Information sourced from Uniprot.org

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