Anti-Dicarbonyl Reductase antibody (C-Term) (STJ70209)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Dicarbonyl Reductase (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 26kDa band observed in human kidney, liver and testes lysates (calculated MW of 25.9kDa according to NP_057370.1). Recommended for use at 0.1-0.3ยตg/ml.IHC: In paraffin embe |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DCXR |
| Gene ID | 51181 |
| Uniprot ID | DCXR_HUMAN |
| Accession Number | NP_057370.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | GSTLPVEGGFWAC |
Additional Info
| Function | Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. |
| Protein Name | L-Xylulose ReductaseXrCarbonyl Reductase IiDicarbonyl/L-Xylulose ReductaseKidney Dicarbonyl ReductaseKidcrShort Chain Dehydrogenase/Reductase Family 20c Member 1Sperm Surface Protein P34h |
| Database Links | Reactome: R-HSA-5661270Reactome: R-HSA-5662853 |
| Cellular Localisation | MembranePeripheral Membrane ProteinProbably Recruited To Membranes Via An Interaction With Phosphatidylinositol |
| Alternative Antibody Names | Anti-L-Xylulose Reductase antibodyAnti-Xr antibodyAnti-Carbonyl Reductase Ii antibodyAnti-Dicarbonyl/L-Xylulose Reductase antibodyAnti-Kidney Dicarbonyl Reductase antibodyAnti-Kidcr antibodyAnti-Short Chain Dehydrogenase/Reductase Family 20c Member 1 antibodyAnti-Sperm Surface Protein P34h antibodyAnti-DCXR antibodyAnti-SDR20C1 antibody |
Information sourced from Uniprot.org