| Host: | Rabbit |
| Applications: | IHC/IF/WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein diaphanous homolog 2 is suitable for use in Immunohistochemistry, Immunofluorescence and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200WB 1:500-2000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DIAPH2 |
| Gene ID: | 1730 |
| Uniprot ID: | DIAP2_HUMAN |
| Specificity: | This antibody detects endogenous levels of human DIAP2 |
| Immunogen: | Synthesized peptide derived from the human DIAP2 |
| Function | Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton. |
| Protein Name | Protein Diaphanous Homolog 2Diaphanous-Related Formin-2Drf2 |
| Database Links | Reactome: R-HSA-5663220Reactome: R-HSA-9013405 O60879-3Reactome: R-HSA-9035034 |
| Cellular Localisation | Isoform 3: CytoplasmCytosolEarly EndosomeIsoform 3 Is Cytosolic But When Coexpressed With RhodThe 2 Proteins Colocalize To Early Endosomes |
| Alternative Antibody Names | Anti-Protein Diaphanous Homolog 2 antibodyAnti-Diaphanous-Related Formin-2 antibodyAnti-Drf2 antibodyAnti-DIAPH2 antibodyAnti-DIA antibody |
Information sourced from Uniprot.org
