| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DIAPH2 (1-120) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DIAPH2 |
| Gene ID: |
1730 |
| Uniprot ID: |
DIAP2_HUMAN |
| Immunogen Region: |
1-120 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DIAPH2 (NP_009293.1). |
| Immunogen Sequence: |
MEQPGAAASGAGGGSEEPGG GRSNKRSAGNRAANEEETKN KPKLNIQIKTLADDVRDRIT SFRKSTVKKEKPLIQHPIDS QVAMSEFPAAQPLYDERSLN LSEKEVLDLFEKMMEDMNLN |
| Tissue Specificity | Expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes. |
| Function | Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton. |
| Protein Name | Protein Diaphanous Homolog 2Diaphanous-Related Formin-2Drf2 |
| Database Links | Reactome: R-HSA-5663220Reactome: R-HSA-9013405 O60879-3Reactome: R-HSA-9035034 |
| Cellular Localisation | Isoform 3: CytoplasmCytosolEarly EndosomeIsoform 3 Is Cytosolic But When Coexpressed With RhodThe 2 Proteins Colocalize To Early Endosomes |
| Alternative Antibody Names | Anti-Protein Diaphanous Homolog 2 antibodyAnti-Diaphanous-Related Formin-2 antibodyAnti-Drf2 antibodyAnti-DIAPH2 antibodyAnti-DIA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
