Anti-DHPS antibody (1-369) (STJ28450)

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STJ28450
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DHPS
Gene ID: 1725
Uniprot ID: DHYS_HUMAN
Immunogen Region: 1-369
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human DHPS (NP_001921.1).
Immunogen Sequence: MEGSLEREAPAGALAAVLKH SSTLPPESTQVRGYDFNRGV NYRALLEAFGTTGFQATNFG RAVQQVNAMIEKKLEPLSQD EDQHADLTQSRRPLTSCTIF LGYTSNLISSGIRETIRYLV QHNMVDVLVTTAGGVEEDLI KCLAPTYLGEFSLRGKELRE NGINRIGNLLVPNENYCKFE DWLMPILDQMVMEQNTEGVK WTPSKMIARLGKEINNPESV YYWAQKNHIPVFSPALTDG
Function Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.
Protein Name Deoxyhypusine Synthase
Dhs
Database Links Reactome: R-HSA-204626
Alternative Antibody Names Anti-Deoxyhypusine Synthase antibody
Anti-Dhs antibody
Anti-DHPS antibody
Anti-DS antibody

Information sourced from Uniprot.org