Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DHPS |
Gene ID: | 1725 |
Uniprot ID: | DHYS_HUMAN |
Immunogen Region: | 1-369 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human DHPS (NP_001921.1). |
Immunogen Sequence: | MEGSLEREAPAGALAAVLKH SSTLPPESTQVRGYDFNRGV NYRALLEAFGTTGFQATNFG RAVQQVNAMIEKKLEPLSQD EDQHADLTQSRRPLTSCTIF LGYTSNLISSGIRETIRYLV QHNMVDVLVTTAGGVEEDLI KCLAPTYLGEFSLRGKELRE NGINRIGNLLVPNENYCKFE DWLMPILDQMVMEQNTEGVK WTPSKMIARLGKEINNPESV YYWAQKNHIPVFSPALTDG |
Function | Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. |
Protein Name | Deoxyhypusine SynthaseDhs |
Database Links | Reactome: R-HSA-204626 |
Alternative Antibody Names | Anti-Deoxyhypusine Synthase antibodyAnti-Dhs antibodyAnti-DHPS antibodyAnti-DS antibody |
Information sourced from Uniprot.org