| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Dihydrofolate reductase 2, mitochondrial (31-81 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DHFR2 |
| Gene ID: | 200895 |
| Uniprot ID: | DYR2_HUMAN |
| Immunogen Region: | 31-81 aa |
| Specificity: | This antibody detects endogenous levels of DYRL1 at Human |
| Immunogen: | Synthesized peptide derived from the human DYRL1 at the amino acid range 31-81 |
| Function | Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR. |
| Protein Name | Dihydrofolate Reductase 2 - MitochondrialDihydrofolate Reductase - MitochondrialDihydrofolate Reductase-Like Protein 1 |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | MitochondrionMitochondrion MatrixMitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Dihydrofolate Reductase 2 - Mitochondrial antibodyAnti-Dihydrofolate Reductase - Mitochondrial antibodyAnti-Dihydrofolate Reductase-Like Protein 1 antibodyAnti-DHFR2 antibodyAnti-DHFRL1 antibodyAnti-DHFRP4 antibody |
Information sourced from Uniprot.org