• Western blot analysis of lysates from HUVEC cells, using DGKD Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using DGK-Delta Polyclonal Antibody

Anti-DGKD antibody (41-90 aa) (STJ92698)

SKU:
STJ92698

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Diacylglycerol kinase delta (41-90 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DGKD
Gene ID: 8527
Uniprot ID: DGKD_HUMAN
Immunogen Region: 41-90 aa
Specificity: DGK-Delta Polyclonal Antibody detects endogenous levels of DGK-Delta protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human DGKD at the amino acid range 41-90
Post Translational Modifications Isoform 1: Phosphorylated. Phosphorylation by PKC induced by phorbol esters prevents homooligomerization and promotes association with membranes.
Function Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). By controlling the levels of diacylglycerol, regulates for instance the PKC and EGF receptor signaling pathways and plays a crucial role during development. May also regulate clathrin-dependent endocytosis.
Protein Name Diacylglycerol Kinase Delta
Dag Kinase Delta
130 Kda Diacylglycerol Kinase
Diglyceride Kinase Delta
Dgk-Delta
Database Links Reactome: R-HSA-114508
Cellular Localisation Membrane
Clathrin-Coated Pit
Cytoplasm
Isoform 1: Cell Membrane
Peripheral Membrane Protein
Isoform 1 Translocation From Cytoplasm To The Plasma Membrane Is Induced By Phorbol Esters
Phorbol Esters Induce The Conversion Into The Monomeric Form Which Can Translocate To The Plasma Membrane
Alternative Antibody Names Anti-Diacylglycerol Kinase Delta antibody
Anti-Dag Kinase Delta antibody
Anti-130 Kda Diacylglycerol Kinase antibody
Anti-Diglyceride Kinase Delta antibody
Anti-Dgk-Delta antibody
Anti-DGKD antibody
Anti-KIAA0145 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance