| Host: |
Rabbit |
| Applications: |
WB/IHC-P/IP |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-DGKA (511-700 aa) is suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
R06-6H4 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: |
Affinity Purified |
| Concentration: |
0.3 mg/ml |
| Dilution Range: |
WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Storage Instruction: |
Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: |
DGKA |
| Gene ID: |
1606 |
| Uniprot ID: |
DGKA_HUMAN |
| Immunogen Region: |
511-700 aa |
| Immunogen: |
Recombinant protein of human DGKA |
| Tissue Specificity | Expressed in lymphocytes. |
| Function | Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids (Probable). Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group. Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol. |
| Protein Name | Diacylglycerol Kinase AlphaDag Kinase Alpha80 Kda Diacylglycerol KinaseDiglyceride Kinase AlphaDgk-Alpha |
| Database Links | Reactome: R-HSA-114508 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Diacylglycerol Kinase Alpha antibodyAnti-Dag Kinase Alpha antibodyAnti-80 Kda Diacylglycerol Kinase antibodyAnti-Diglyceride Kinase Alpha antibodyAnti-Dgk-Alpha antibodyAnti-DGKA antibodyAnti-DAGK antibodyAnti-DAGK1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
