Anti-DGKA antibody (511-700 aa) [R06-6H4] (STJA0012346)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human DGKA
General Information
| Short Description | Rabbit monoclonal anti-DGKA (511-700 aa) for use in WB, IHC-P and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-6H4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DGKA |
| Gene ID | 1606 |
| Uniprot ID | DGKA_HUMAN |
| Immunogen | Recombinant protein of human DGKA |
| Immunogen Region | 511-700 aa |
Additional Info
| Tissue Specificity | Expressed in lymphocytes. |
| Function | Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids (Probable). Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group. Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol. |
| Protein Name | Diacylglycerol Kinase AlphaDag Kinase Alpha80 Kda Diacylglycerol KinaseDiglyceride Kinase AlphaDgk-Alpha |
| Database Links | Reactome: R-HSA-114508 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Diacylglycerol Kinase Alpha antibodyAnti-Dag Kinase Alpha antibodyAnti-80 Kda Diacylglycerol Kinase antibodyAnti-Diglyceride Kinase Alpha antibodyAnti-Dgk-Alpha antibodyAnti-DGKA antibodyAnti-DAGK antibodyAnti-DAGK1 antibody |
Information sourced from Uniprot.org