| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DFFA (1-331) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DFFA |
| Gene ID: |
1676 |
| Uniprot ID: |
DFFA_HUMAN |
| Immunogen Region: |
1-331 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human DFFA (NP_004392.1). |
| Immunogen Sequence: |
MEVTGDAGVPESGEIRTLKP CLLRRNYSREQHGVAASCLE DLRSKACDILAIDKSLTPVT LVLAEDGTIVDDDDYFLCLP SNTKFVALASNEKWAYNNSD GGTAWISQESFDVDETDSGA GLKWKNVARQLKEDLSSIIL LSEEDLQMLVDAPCSDLAQE LRQSCATVQRLQHTLQQVLD QREEVRQSKQLLQLYLQALE KEGSLLSKQEESKAAFGEEV DAVDTGISRETSSDVALAS |
| Post Translational Modifications | Caspase-3 cleaves DFF45 at 2 sites to generate an active factor. |
| Function | Inhibitor of the caspase-activated DNase (DFF40). |
| Protein Name | Dna Fragmentation Factor Subunit AlphaDna Fragmentation Factor 45 Kda SubunitDff-45Inhibitor Of CadIcad |
| Database Links | Reactome: R-HSA-140342 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Dna Fragmentation Factor Subunit Alpha antibodyAnti-Dna Fragmentation Factor 45 Kda Subunit antibodyAnti-Dff-45 antibodyAnti-Inhibitor Of Cad antibodyAnti-Icad antibodyAnti-DFFA antibodyAnti-DFF1 antibodyAnti-DFF45 antibodyAnti-H13 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunofluorescence analysis of HeLa cells using [KO Validated] DFFA Rabbit polyclonal antibody (STJ29835). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/102903/392132/STJ29835_1__60621.1713162515.jpg?c=1 "Immunofluorescence analysis of HeLa cells using [KO Validated] DFFA Rabbit polyclonal antibody (STJ29835). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
