| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DFFA |
| Gene ID: | 1676 |
| Uniprot ID: | DFFA_HUMAN |
| Immunogen Region: | 1-331 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human DFFA (NP_004392.1). |
| Immunogen Sequence: | MEVTGDAGVPESGEIRTLKP CLLRRNYSREQHGVAASCLE DLRSKACDILAIDKSLTPVT LVLAEDGTIVDDDDYFLCLP SNTKFVALASNEKWAYNNSD GGTAWISQESFDVDETDSGA GLKWKNVARQLKEDLSSIIL LSEEDLQMLVDAPCSDLAQE LRQSCATVQRLQHTLQQVLD QREEVRQSKQLLQLYLQALE KEGSLLSKQEESKAAFGEEV DAVDTGISRETSSDVALAS |
| Post Translational Modifications | Caspase-3 cleaves DFF45 at 2 sites to generate an active factor. |
| Function | Inhibitor of the caspase-activated DNase (DFF40). |
| Protein Name | Dna Fragmentation Factor Subunit AlphaDna Fragmentation Factor 45 Kda SubunitDff-45Inhibitor Of CadIcad |
| Database Links | Reactome: R-HSA-140342 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Dna Fragmentation Factor Subunit Alpha antibodyAnti-Dna Fragmentation Factor 45 Kda Subunit antibodyAnti-Dff-45 antibodyAnti-Inhibitor Of Cad antibodyAnti-Icad antibodyAnti-DFFA antibodyAnti-DFF1 antibodyAnti-DFF45 antibodyAnti-H13 antibody |
Information sourced from Uniprot.org