• Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-DENND1A antibody (14-64 aa) (STJ195500)

SKU:
STJ195500

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DENN domain-containing protein 1A (14-64 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DENND1A
Gene ID: 57706
Uniprot ID: DEN1A_HUMAN
Immunogen Region: 14-64 aa
Specificity: This antibody detects endogenous levels of DEN1A at Human/Mouse
Immunogen: Synthesized peptide derived from the human DEN1A at the amino acid range 14-64
Function Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes. Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P.
Protein Name Denn Domain-Containing Protein 1a
Connecdenn 1
Connecdenn
Protein Fam31a
Database Links Reactome: R-HSA-8876198
Cellular Localisation Cytoplasmic Vesicle
Clathrin-Coated Vesicle Membrane
Peripheral Membrane Protein
Presynaptic Cell Membrane
Associates To Membranes Via Lipid-Binding Activity
Alternative Antibody Names Anti-Denn Domain-Containing Protein 1a antibody
Anti-Connecdenn 1 antibody
Anti-Connecdenn antibody
Anti-Protein Fam31a antibody
Anti-DENND1A antibody
Anti-FAM31A antibody
Anti-KIAA1608 antibody

Information sourced from Uniprot.org

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