| Short Description : | Rabbit polyclonal DECR2 (140-240) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DECR2 |
| Gene ID: | 26063 |
| Uniprot ID: | DECR2_HUMAN |
| Immunogen Region: | 140-240 |
| Immunogen Sequence: | GTFNVSRVLYEKFFRDHGGV IVNITATLGNRGQALQVHAG SAKAAVDAMTRHLAVEWGPQ NIRVNSLAPGPISGTEGLRR LGGPQASLSTKVTASPLQRL G |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DECR2 (NP_065715.1). |
| Function | Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. |
| Protein Name | Peroxisomal 2 -4-Dienoyl-Coa Reductase (3e-Enoyl-Coa-ProducingPdcr2 -4-Dienoyl-Coa Reductase 2Short Chain Dehydrogenase/Reductase Family 17c Member 1 |
| Database Links | Reactome: R-HSA-390247Reactome: R-HSA-9033241 |
| Cellular Localisation | Peroxisome |
| Alternative Antibody Names | Anti-Peroxisomal 2 -4-Dienoyl-Coa Reductase (3e-Enoyl-Coa-Producing antibodyAnti-Pdcr antibodyAnti-2 -4-Dienoyl-Coa Reductase 2 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 17c Member 1 antibodyAnti-DECR2 antibodyAnti-PDCR antibodyAnti-SDR17C1 antibody |
Information sourced from Uniprot.org
